Dog FaSSIF/Dog FaSSGF: Product Benefits

Biorelevant Media simulate gut fluids before (fasted) and after (fed) eating food. They are really useful for predicting what will happen to your product when it enters the gastro-intestinal tract. In the past the media were notoriously difficult to prepare.

In 2007 we solved this problem by inventing a product that makes Biorelevant Media instantly. This year we’ve introduced a new line that simulates a dog's stomach and small intestinal fluid in the fasted state. The physiology of dogs and humans is very different and this is reflected in the modified compositions of Dog FaSSIF and Dog FaSSGF*.

There are so many benefits to using our product to make these dog media:

Quick and easy to use

Add powder to buffer and you're ready to go...

Reproducible results

We use only the highest grade of ingredients and double check their purity before manufacture. The powders are made in our own facility in London so we can control every aspect of their production. Once this process is complete, they are only released after rigorous analysis by an independent laboratory in Germany. These high levels of quality control ensure you will get consistent, highly reproducible results from our products every time.

Great value

2 bottle sizes are available so whether you want to make 10 mL or 100 L of Dog FaSSIF, we can satisfy your requirements. The powder has a long shelf life of 18 months so there is no need for any waste. We also offer money-saving 4 packs.

"Dog FaSSGF and Dog FaSSIF helped us to select one formulation out of several prototypes for a bioavailability study in dogs. All prototypes were tested in buffer media in advance but results were hardly discriminative due to the poor solubility of the API. We expect that the canine biorelevant media will also reflect the in vivo precipitation kinetics of APIs more accurately if enhanced solubility (supersaturation) is targeted.”

Dr. Marcel Arndt, 
Head of Dissolution Laboratory,
 Evonik Nutrition & Care GmbH

*Marcel Arndt et al.: Dissolution media simulating the proximal canine gastrointestinal tract in the fasted state (2013)