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FaSSIF/FeSSIF/FaSSGF

  • Use 3F Powder + Buffer Concentrates to make FaSSIF/FeSSIF/FaSSGF

  • 3F Powder contains bile salts + lecithin to form gastrointestinal mixed micelles

  • Buffer Concentrates make up the 3 different buffer solutions in seconds

  • Use Media Preparation Tool below for customized preparation instructions

1) Buy Powder:

  • Use with diluted Buffer Concentrates (available below) for instant media prep

  • 3F Powder (70g) makes FaSSIF (30L) or FeSSIF (6L) or FaSSGF (>1000L)

3F Powder 7g
Product Code: FFF01
3F Powder 70g
Product Code: FFF02
Quantity
1+
$139.99
4+
$99.99
Save 29%
1+
$499.99
4+
$399.99
Save 21%
-
+
Total: $
$/Unit
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Email Purchase Orders to [email protected]. Please include:

- A Purchase Order Number
- Shipping info: address, contact name, email and telephone
- Billing info: address, contact name, email and telephone

First orders will trigger a proforma invoice for pre-payment.
30 days net terms will apply to subsequent purchases.
Send Purchase Order
In stock
In stock
BEST SELLER

1) Buy Powder:

  • Use with diluted Buffer Concentrates (available below) for instant media prep

  • 3F Powder (70g) makes FaSSIF (30L) or FeSSIF (6L) or FaSSGF (>1000L)

3F Powder 7g
Product Code: FFF01
3F Powder 70g
Product Code: FFF02
Quantity
1+
$139.99
Save 0%
4+
$99.99
Save 29%
1+
$499.99
Save 0%
4+
$399.99
Save 21%
-
+
Total: $
$/Unit
Add to Cart
X

To get quote add to cart item(s) you require.

Get Quote
Get Quote
Send Purchase Order
X
Email Purchase Orders to [email protected]. Please include:

- A Purchase Order Number
- Shipping info: address, contact name, email and telephone
- Billing info: address, contact name, email and telephone

First orders will trigger a proforma invoice for pre-payment.
30 days net terms will apply to subsequent purchases.

2) Choose Buffer Concentrates:

  •  Must be used in combination with 3F Powder (available above)

  • 250g of Buffer Concentrate in each bottle

FaSSIF Buffer Conc 6L
Product Code: FASBUF
FeSSIF Buffer Conc 3L
Product Code: FESBUF
FaSSGF Buffer Conc 6L
Product Code: FASGBUF
Quantity
1+
$29.99
10+
$26.99
Save 11%
1+
$29.99
10+
$26.99
Save 11%
1+
$29.99
10+
$26.99
Save 11%
-
+
Total: $
$/Unit
X

To get quote add to cart item(s) you require.

Add to Cart
Get Quote
Get Quote
X
Email Purchase Orders to [email protected]. Please include:

- A Purchase Order Number
- Shipping info: address, contact name, email and telephone
- Billing info: address, contact name, email and telephone

First orders will trigger a proforma invoice for pre-payment.
30 days net terms will apply to subsequent purchases.
Send Purchase Order
In stock
In stock

2) Choose Buffer Concentrates:

Product Code:
  •  Must be used in combination with 3F Powder (available above)

  • 250g of Buffer Concentrate in each bottle

FaSSIF Buffer Conc 6L
Product Code: FASBUF
FeSSIF Buffer Conc 3L
Product Code: FESBUF
FaSSGF Buffer Conc 6L
Product Code: FASGBUF
Quantity
1+
$29.99
Save 0%
10+
$26.99
Save 11%
1+
$29.99
Save 0%
10+
$26.99
Save 11%
1+
$29.99
Save 0%
10+
$26.99
Save 11%
-
+
Total: $
$/Unit
Add to Cart
X

To get quote add to cart item(s) you require.

Get Quote
Get Quote
Send Purchase Order
X
Email Purchase Orders to [email protected]. Please include:

- A Purchase Order Number
- Shipping info: address, contact name, email and telephone
- Billing info: address, contact name, email and telephone

First orders will trigger a proforma invoice for pre-payment.
30 days net terms will apply to subsequent purchases.

3) Add Syringe Filters:

  • We recommend Polypropylene Syringe Filters for testing in FaSSIF & FaSSGF

  • We recommend Glass Microfibre Syringe Filters for testing in FeSSIF

  • Available for immediate dispatch in packs of 6 pieces

Polypropylene (6 pieces)
Product Code: SF-PP-6
Glass Microfibre (6 pieces)
Product Code: SF-GMF-6
Quantity
-
+
Total: $
$/Unit
X

To get quote add to cart item(s) you require.

Add to Cart
Get Quote
Get Quote
X
Email Purchase Orders to [email protected]. Please include:

- A Purchase Order Number
- Shipping info: address, contact name, email and telephone
- Billing info: address, contact name, email and telephone

First orders will trigger a proforma invoice for pre-payment.
30 days net terms will apply to subsequent purchases.
Send Purchase Order
In stock
In stock

3) Add Syringe Filters:

Product Code:
  • We recommend Polypropylene Syringe Filters for testing in FaSSIF & FaSSGF

  • We recommend Glass Microfibre Syringe Filters for testing in FeSSIF

  • Available for immediate dispatch in packs of 6 pieces

Polypropylene (6 pieces)
Product Code: SF-PP-6
Glass Microfibre (6 pieces)
Product Code: SF-GMF-6
Quantity
-
+
Total: $
$/Unit
Add to Cart
X

To get quote add to cart item(s) you require.

Get Quote
Get Quote
Send Purchase Order
X
Email Purchase Orders to [email protected]. Please include:

- A Purchase Order Number
- Shipping info: address, contact name, email and telephone
- Billing info: address, contact name, email and telephone

First orders will trigger a proforma invoice for pre-payment.
30 days net terms will apply to subsequent purchases.
Media Preparation Tool
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Product Description

FaSSIF, FeSSIF and FaSSGF are dissolution media that simulate human gut fluids:

FaSSIF: Fasted State Simulated Intestinal Fluid
FeSSIF: Fed State Simulated Intestinal Fluid
FaSSGF: Fasted State Simulated Gastric Fluid

They contain physiological surfactants (bile salts and lecithin) present in the gastrointestinal tract to simulate these fluids much more accurately than conventional dissolution media.

We’ve been producing FaSSIF/FeSSIF/FaSSGF (originally known as ‘SIF Powder’) for more than a decade and it’s trusted by the 10 biggest Pharmaceutical companies in the world as the industrial standard for preparing biorelevant test media. Its versatility and ease of use make it the perfect introduction to biorelevant testing. Here’s why the product is so useful to both new and generic developers of oral drugs:

*In vitro solubility results in biorelevant media help establish a relationship between the biopharmaceutical properties of an oral drug and in vivo absorption

*In vitro dissolution results in biorelevant media can enable drug developers to identify test formulations with superior dissolution profiles

*Ideal for use in USP 1 or USP 2 dissolution apparatus (we recommend 900mL of media per vessel)

*Drug analysis can be carried out by HPLC

*Standardized preparation method is extremely fast and simple and results in highly reproducible media every time

*Get customized instructions explaining how to make different FaSSIF/FeSSIF/FaSSGF volumes from our ‘Media Preparation Tool’ (see above)

Frequently bought together with FaSSIF/FeSSIF/FaSSGF
FEDGAS
Simulates fed state gastric fluids. Excellent discriminatory power for neutral, basic or acidic BCS Class 2 drugs
Frequently bought together with FaSSIF/FeSSIF/FaSSGF
FEDGAS
Simulates fed state gastric fluids. Excellent discriminatory power for neutral, basic or acidic BCS Class 2 drugs