Learning Centre

ALL NEW! Background Biorelevant media Analysis Filters Dissolution tips Guides and Calcs Dissolution
Tip Image
NEW!
Dissolution tips

Two stage biorelevant dissolution

This in vitro experiment simulates the in vivo process when fasted stomach fluid (FaSSGF) containing a drug product is converted to fasted intestinal fluid (FaSSIF).
Tip Image
NEW!
Dissolution tips

pH reproducibility of two Stage biorelevant dissolution kit

Learn about pH of FaSSGF and FaSSIF prepared from the Two Stage Biorelevant Dissolution
Tip Image
Biorelevant media
Dissolution tips

How can biorelevant media be discriminatory?

When selected and used correctly, Biorelevant Media are perfect discriminatory dissolution tools for evaluating a Test formulation against the Originator.
Tip Image
Dissolution tips

Biorelevant Dissolution Test Method

Our biorelevant dissolution test method uses standardized USP apparatus and works for most immediate release oral dosage forms (e.g. BCS Class 2 or 4 drugs).
Tip Image
Dissolution tips

Dissolution profiles in FaSSIF-V2

Ibuprofen, Carbamazepine and Diclofenac dissolution profiles in FaSSIF-V2 made using FaSSIF-V2 Powder + Buffer Concentrate.
Tip Image
Dissolution tips

Dissolution profiles in FeSSIF-V2

Dissolution runs, using USP Dissolution Apparatus 2, were carried out at 37°C with 900mL of the FeSSIF-V2 media.
Tip Image
Biorelevant media
Dissolution tips

What is Canine FaSSIF and Canine FaSSGF?

Learn about the three types of canine biorelevant media
Tip Image
Dissolution tips

Coning of immediate release drug products in a USP 2

Coning of immediate release drug products is a problem
Tip Image
Dissolution tips

What are the signs of coning

Signs and examples of coning in a USP 2 dissolution vessel
Tip Image
Dissolution tips

PEAK (Apex) dissolution vessels

This post explains what PEAK (Apex) vessels