What is in FEDGAS?

FEDGAS in vitro test solutions simulate stomach fluids after consumption of a high-fat FDA meal. The FDA meal is frequently co-administered with drugs in human clinical trials to assess potential food effects on a drug’s pharmacokinetics by eliciting an extreme physiological response in the gut. 900mL of FEDGAS medium contains the same amount of fat present in this meal.The three different types of FEDGAS (early, mid and late) represent fluids from different stages of stomach emptying (pH 3, pH 4.5 and pH 6 respectively). FEDGAS also replicates the dietary fibre and carbohydrate content of the FDA meal. Bile salt that is refluxed back into the stomach from the upper section of the small intestine during digestion is mimicked too. The composition of FEDGAS is provided here:

You can buy FEDGAS or get more information on it here.