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The home of biorelevant media (FaSSIF, FeSSIF)

News

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FREE T-Shirts with 3+1 Promotion!

This Summer we’re giving away FREE exclusive biorelevant.com t-shirts with every SIF Powder 3 ...

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New Biorelevant Media Cartoon!

If you're new to Biorelevant Media, or perhaps want to explain what they are to ...

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Recent Publications Using SIF Powder

Click the following link to view numerous 'biorelevant' publications where SIF Powder has been used to ...

What we do

Most drugs are taken orally, for example as tablets or capsules. Understanding how they are taken up from the gastrointestinal tract into the body can help predict their performance in patients. The problem is that compendial test media (such as simulated intestinal fluid usp) do not mimic the highly variable and dynamic environment of the human gut accurately enough. But biorelevant dissolution media do! They contain physiologically relevant surfactants (Bile Salts and Phospholipids) which make them extremely similar to juices inside the stomach and small intestine. Testing your oral drug in vitro in biorelevant dissolution media can therefore give a far more accurate indication of how it’s likely to dissolve and release in vivo. You are consequently much more likely to establish IVIVCs (in vitro in vivo correlations). Our patented range of powders enables you to produce different types of biorelevant media (FaSSIF, FeSSIF, FaSSGF, FaSSIF-V2 and FeSSIF-V2) with ease and we’ve been supplying them to companies, universities and institutes all over the world since 2007. They are available to buy from this website.

Our products

Image SIF Powder Original

SIF Powder Original

Makes FaSSIF, FeSSIF
and FaSSGF

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Image SIF Powder FaSSIF-V2

SIF Powder FaSSIF-V2

Makes FaSSIF-V2

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