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The home of biorelevant media (FaSSIF, FeSSIF)

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News

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FeSSIF-V2 Powder Launched

We are delighted to announce the launch of FeSSIF-V2 Powder. This second generation of fed state ...

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Greetings to our AAPS San Diego Visitors!

A big welcome to the many visitors who dropped by our booth (3701) at the recent ...

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New Names and Labels for our Powders

We have recently decided to change the names of our SIF Powder products. Our pack sizes ...

Biorelevant dissolution media

Most drugs are taken orally, for example as tablets or capsules. Understanding how they are taken up from the gastrointestinal tract into the body can help predict their performance in patients. The problem is that compendial test media (such as simulated intestinal fluid usp) do not mimic the highly variable and dynamic environment of the human gut accurately enough. But biorelevant dissolution media do! They contain physiologically relevant surfactants (bile salts and phospholipids) which make them extremely similar to juices inside the stomach and small intestine. Furthermore, there are biorelevant media to reflect both fasted and fed state GI fluids; this can enable you to investigate food effects. Testing your oral drug in vitro in biorelevant dissolution media can therefore give a far more accurate indication of how it’s likely to dissolve and release in vivo so you are much more likely to establish IVIVCs (in vitro in vivo correlations). Our patented range of powders enables you to produce different types of biorelevant media (FaSSIF, FeSSIF, FaSSGF, FaSSIF-V2 and FeSSIF-V2) with ease and we’ve been supplying them to companies, universities and institutes all over the world since 2007. They are available to buy from this website.

Our products

Image FaSSIF, FeSSIF & FaSSGF Powder

FaSSIF, FeSSIF & FaSSGF Powder

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Image FaSSIF-V2 Powder

FaSSIF-V2 Powder

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Image FeSSIF-V2 Powder

FeSSIF-V2 Powder

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