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Product Description
FeSSIF-V2 is a biorelevant dissolution medium that simulates human fed state intestinal fluid. It is quite similar to FeSSIF but contains lipolysis products of fat digestion. This could help you understand more clearly the solubility and dissolution of lipophilic drugs (Log D ≥ 3) in the fed state intestine in vivo. It’s a very useful tool for new and generic developers of an oral drug:
*FeSSIF-V2 is described in the recently introduced ‘USP Chapter <1236> Solubility measurements’ as a recommended biorelevant medium for testing drug solubility in human fed state simulated intestinal fluid
*Ideal for use in USP 1 or USP 2 dissolution apparatus (we recommend 900ml of FeSSIF-V2 per vessel)
*Drug analysis can be carried out by HPLC
*Simple and quick preparation method
*Get customized instructions explaining how to make different FeSSIF-V2 volumes from our ‘Media Preparation Tool’ (see above)
*Different pack sizes available to suit your testing requirements (see top of screen)