FeSSIF-V2

  • Use FeSSIF-V2 Powder with matching Buffer Concentrate for instant medium preparation and maximum reproducibility

  • V2FES (60g Powder) make 6 litres of FeSSIF-V2 dissolution medium

  • V2FESBUF (310g Buffer Concentrate) make 6 litres of buffer

  • Custom Syringe Filters available in packs of 36 pieces

  • Use Media Preparation Tool below for customized preparation instructions

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1) Buy Powder:

FeSSIF-V2 Powder
Buy 4, Save 20%
V2FES
60g
- +
$499.99
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In stock

2) Buy Buffer Concentrate:

FeSSIF-V2 Buffer Concentrate
V2FESBUF
310g
- +
$29.99
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In stock
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3) Add Syringe Filters (36 per pack):

  • For filtration of dissolution samples <5mL we recommend 13mm version

  • For filtration of dissolution samples >5mL we recommend 25mm version

GMF Syringe Filters 13mm
Buy 4, Save 20%
GMF-13
36 pieces
GMF Syringe Filters 25mm
Buy 4, Save 20%
GMF-25
36 pieces
- +
$99.99
- +
$99.99
Media Preparation Tool
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Product Description

FeSSIF-V2 is a biorelevant dissolution medium that simulates human fed state intestinal fluid. It is quite similar to FeSSIF but contains lipolysis products of fat digestion. This could help you understand more clearly the solubility and dissolution of lipophilic drugs (Log D ≥ 3) in the fed state intestine in vivo. It’s a very useful tool for new and generic developers of an oral drug:

*FeSSIF-V2 is described in the recently introduced ‘USP Chapter <1236> Solubility measurements’ as a recommended biorelevant medium for testing drug solubility in human fed state simulated intestinal fluid

*Ideal for use in USP 1 or USP 2 dissolution apparatus (we recommend 900ml of FeSSIF-V2 per vessel)

*Drug analysis can be carried out by HPLC

*Simple and quick preparation method

*Get customized instructions explaining how to make different FeSSIF-V2 volumes from our ‘Media Preparation Tool’ (see above)