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What is FaSSIF?
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FaSSIF (Fasted State Simulated Intestinal Fluid) is a very useful drug development tool. Tests in this dissolution medium can reveal …
What is FeSSIF?
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FeSSIF (Fed State Simulated Intestinal Fluid) is a very useful drug development tool. Tests in this dissolution medium can help …
What is FaSSGF?
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FaSSGF (Fasted State Simulated Gastric Fluid) is a very useful drug development tool. Tests in this dissolution medium can help …
What is FEDGAS?
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FEDGAS (Fed State Simulated Gastric Fluid AKA FeSSGF) is a very useful drug development tool. Tests in these dissolution media …
FeSSGF vs FEDGAS: a comparison
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In vitro dissolution testing of drugs in media that simulate in vivo gastric fluids after a meal can be very …
How to analyse your drug in Biorelevant Media
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After drug separation, the medium (containing dissolved drug) is best analysed by HPLC. HPLC avoids potential interference of the media and can identify possible drug instability
How biorelevant media can help develop new drugs (NCEs)
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Whether you're a chemist, biologist or pharmacist involved in the development a new oral drug (NCE: New Chemical Entity), biorelevant …
Composition and physico-chemical properties of FaSSIF-V2
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An improved buffer concentrate for preparation of FaSSIF-V2 has been developed to overcome the limitations of the previous maleic acid buffer system.
HPLC Parameters using FaSSIF-V2
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Comparing HPLC profiles of FaSSIF-V2 made using Buffer Concentrate versus FaSSIF-V2 made using buffer from scratch
Dissolution profiles in FaSSIF-V2
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Ibuprofen, Carbamazepine and Diclofenac dissolution profiles in FaSSIF-V2
Composition and physico-chemical properties of FeSSIF-V2
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An improved Buffer Concentrate for preparation of FeSSIF-V2 has been developed to overcome the limitations of the previous maleic acid buffer system.