BEST SELLER

FaSSIF/FeSSIF/FaSSGF

  • Use 3F Powder + Buffer Concentrates to make FaSSIF/FeSSIF/FaSSGF

  • 3F Powder contains bile salts + lecithin to form gastrointestinal mixed micelles

  • Buffer Concentrates make up the 3 different buffer solutions in seconds

  • Use Media Preparation Tool below for customized preparation instructions

1) Buy Powder:

  • Use with diluted Buffer Concentrates (available below) for instant media prep

  • 3F Powder (70g) makes FaSSIF (30L) or FeSSIF (6L) or FaSSGF (>1000L)

3F Powder (FaSSIF/FeSSIF/FaSSGF)
*NOW 20% MORE POWDER!*
Product Code: FFF01
3F Powder (70g)
*NOW 20% MORE POWDER!*
Product Code: FFF02
Quantity
1+
$139.99
4+
$99.99
Save 29%
1+
$499.99
4+
$399.99
Save 21%
-
+
Total: $
$/Unit
Add to Cart
Get Quote
Get Quote
X
Email Purchase Orders to: [email protected]
First orders are on a proforma basis.
Subsequent orders qualify for 30 days net payment terms.
Send Purchase Order
BEST SELLER

1) Buy Powder:

  • Use with diluted Buffer Concentrates (available below) for instant media prep

  • 3F Powder (70g) makes FaSSIF (30L) or FeSSIF (6L) or FaSSGF (>1000L)

3F Powder (FaSSIF/FeSSIF/FaSSGF)
*NOW 20% MORE POWDER!*
Product Code: FFF01
3F Powder (70g)
*NOW 20% MORE POWDER!*
Product Code: FFF02
Quantity
1+
$139.99
Save 0%
4+
$99.99
Save 29%
1+
$499.99
Save 0%
4+
$399.99
Save 21%
-
+
Total: $
$/Unit
Add to Cart
Get Quote
Get Quote
Send Purchase Order
X
Email Purchase Orders to: [email protected]
First orders are on a proforma basis.
Subsequent orders qualify for 30 days net payment terms.

2) Choose Buffer Concentrates:

  •  Must be used in combination with 3F Powder (available above)

  • 250g of Buffer Concentrate in each bottle

FaSSIF Buffer Conc (6L)
Product Code: FASBUF
FeSSIF Buffer Conc (3L)
Product Code: FESBUF
FaSSGF Buffer Conc (6L)
Product Code: FASGBUF
Quantity
1+
$29.99
10+
$26.99
Save 11%
1+
$29.99
10+
$26.99
Save 11%
1+
$29.99
10+
$26.99
Save 11%
-
+
Total: $
$/Unit
Add to Cart
Get Quote
Get Quote
X
Email Purchase Orders to: [email protected]
First orders are on a proforma basis.
Subsequent orders qualify for 30 days net payment terms.
Send Purchase Order

2) Choose Buffer Concentrates:

Product Code:
  •  Must be used in combination with 3F Powder (available above)

  • 250g of Buffer Concentrate in each bottle

FaSSIF Buffer Conc (6L)
Product Code: FASBUF
FeSSIF Buffer Conc (3L)
Product Code: FESBUF
FaSSGF Buffer Conc (6L)
Product Code: FASGBUF
Quantity
1+
$29.99
Save 0%
10+
$26.99
Save 11%
1+
$29.99
Save 0%
10+
$26.99
Save 11%
1+
$29.99
Save 0%
10+
$26.99
Save 11%
-
+
Total: $
$/Unit
Add to Cart
Get Quote
Get Quote
Send Purchase Order
X
Email Purchase Orders to: [email protected]
First orders are on a proforma basis.
Subsequent orders qualify for 30 days net payment terms.

3) Add Syringe Filters:

  • We recommend Polypropylene Syringe Filters for testing in FaSSIF & FaSSGF

  • We recommend Glass Microfibre Syringe Filters for testing in FeSSIF

  • Available for immediate dispatch in packs of 6 pieces

Polypropylene (6 pieces)
Product Code: SF-PP-6
Glass Microfibre (6 pieces)
Product Code: SF-GMF-6
Quantity
1+
$19.99
5+
$17.99
Save 11%
1+
$19.99
5+
$17.99
Save 11%
-
+
Total: $
$/Unit
Add to Cart
Get Quote
Get Quote
X
Email Purchase Orders to: [email protected]
First orders are on a proforma basis.
Subsequent orders qualify for 30 days net payment terms.
Send Purchase Order

3) Add Syringe Filters:

Product Code:
  • We recommend Polypropylene Syringe Filters for testing in FaSSIF & FaSSGF

  • We recommend Glass Microfibre Syringe Filters for testing in FeSSIF

  • Available for immediate dispatch in packs of 6 pieces

Polypropylene (6 pieces)
Product Code: SF-PP-6
Glass Microfibre (6 pieces)
Product Code: SF-GMF-6
Quantity
1+
$19.99
Save 0%
5+
$17.99
Save 11%
1+
$19.99
Save 0%
5+
$17.99
Save 11%
-
+
Total: $
$/Unit
Add to Cart
Get Quote
Get Quote
Send Purchase Order
X
Email Purchase Orders to: [email protected]
First orders are on a proforma basis.
Subsequent orders qualify for 30 days net payment terms.
Media Preparation Tool
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Product Description

FaSSIF, FeSSIF and FaSSGF are dissolution media that simulate human gut fluids:

FaSSIF: Fasted State Simulated Intestinal Fluid
FeSSIF: Fed State Simulated Intestinal Fluid
FaSSGF: Fasted State Simulated Gastric Fluid

They contain physiological surfactants (bile salts and lecithin) present in the gastrointestinal tract to simulate these fluids much more accurately than conventional dissolution media.

We’ve been producing FaSSIF/FeSSIF/FaSSGF (originally known as ‘SIF Powder’) for more than a decade and it’s trusted by the 10 biggest Pharmaceutical companies in the world as the industrial standard for preparing biorelevant test media. Its versatility and ease of use make it the perfect introduction to biorelevant testing. Here’s why the product is so useful to both new and generic developers of oral drugs:

*In vitro solubility results in biorelevant media help establish a relationship between the biopharmaceutical properties of an oral drug and in vivo absorption

*In vitro dissolution results in biorelevant media can enable drug developers to identify test formulations with superior dissolution profiles

*Ideal for use in USP 1 or USP 2 dissolution apparatus (we recommend 900mL of media per vessel)

*Drug analysis can be carried out by HPLC

*Standardized preparation method is extremely fast and simple and results in highly reproducible media every time

*Get customized instructions explaining how to make different FaSSIF/FeSSIF/FaSSGF volumes from our ‘Media Preparation Tool’ (see above)