Biorelevant Media simulate the fluids present in the gut before (fasted) and after (fed) eating food. They are really useful tools for predicting what will happen to your product after it’s swallowed. Their close similarity to what's actually inside your body makes them very helpful for Pharmaceutical companies (CROs, developers, generic drug manufacturers) and also the functional food, vitamin and medical device industries. There are even versions available to mimic the gastro-intestinal juices of different animals! We supply the powders which enable you to make Biorelevant Media quickly, easily and cost effectively.
Magnetic marker monitoring
Have you ever wondered if it’s possible to track the passage of an oral dosage form through the gut in real-time? If so, magnetic marker monitoring can do this. It’s a recent technology that can be incorporated into oral dosage forms to monitor the real time location of the dosage form in the gastrointestinal tract¹.
Fed vs Fasted State Performance: Trospium Chloride (OrBiTo)
Solubility of drugs in water, or even aqueous buffers, is often very different to that in gut fluids. This has a simple explanation: there is a complex interplay of different components in the gut which affects drugs very differently compared to plain water. According to the Biopharmaceutics Classification System (BCS), different drugs are classified by
What Are Dog Biorelevant Media And Why Should We Use Them?
Biorelevant Media aim to simulate the gastrointestinal (GI) tract as closely as possible. This opens a world of possibilities when it comes to testing the effect of different foods, devices, drugs and practically anything that enters the GI tract. It has proven particularly useful for drug dissolution and solubility testing, which are key tests when