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ALL NEW! Background Analysis Dissolution Filters Biorelevant media
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Dissolution
Biorelevant media

How food can affect drugs in the FED stomach

In patients with a healthy stomach, a high-fat meal can have multiple...
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Dissolution
Biorelevant media

Biorelevant Media: Discriminatory Dissolution Tools

Interaction of formulations with physiological components of Biorelevant Media mimic wetting and dissolution processes that occur in vivo
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Dissolution

How to carry out Biorelevant Dissolution

The test is based around USP Chapter <1092> 'The Dissolution Procedure' but it's specifically designed for BCS Class 2 drugs in any Biorelevant Media
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Dissolution

Dissolution profiles in FaSSIF-V2

Ibuprofen, Carbamazepine and Diclofenac dissolution profiles in FaSSIF-V2
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Dissolution

Dissolution profiles in FeSSIF-V2

Dissolution runs, using USP Dissolution Apparatus 2, were carried out at 37°C with 900mL of the FeSSIF-V2 media.
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Dissolution

Two stage biorelevant dissolution

This in vitro experiment simulates the in vivo process when fasted stomach fluid (FaSSGF) containing a drug product is converted to fasted intestinal fluid (FaSSIF).
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Dissolution

Coning of immediate release drug products in a USP 2

Coning of immediate release drug products is a problem
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Dissolution

What are the signs of coning

Signs and examples of coning in a USP 2 dissolution vessel
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Dissolution

PEAK (Apex) dissolution vessels

This post explains what PEAK (Apex) vessels
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Dissolution

pH reproducibility of Two Stage Biorelevant Dissolution Kit

Learn about pH of FaSSGF and FaSSIF prepared from the Two Stage Biorelevant Dissolution Kit
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Dissolution
Biorelevant media

What is Canine FaSSIF and Canine FaSSGF?

Learn about the three types of canine biorelevant media