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Biorelevant Mini Prep Kits

FaSSIF/FeSSIF/FaSSGF

FEDGAS (Early/Mid/Late)

Canine FaSSIF/FaSSGF

Biorelevant Dissolution Filters

Biorelevant Solubility Filters

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HPLC Calculators

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ALL NEW! Background Biorelevant media Analysis Filters Dissolution tips Guides and Calcs Dissolution Solubility

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Filters for biorelevant solubility testing

Biorelevant equilibrium solubility testing is a crucial biopharmaceutical parameter

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Filters for two stage dissolution testing

This post describes filters designed for two stage dissolution testing

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Importance of filtration in dissolution sample preparation for HPLC analysis

Filtration is a crucial step in preparing a dissolution sample. It involves passing the sample through a filter to separate solid particles or undissolved materials...

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When is a filter adsorption study necessary?

Filter adsorption studies should always be conducted before dissolution studies are carried out when a) a new drug is being tested or b) a different biorelevant medium is being used.

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Single vs repeated use of filters for two stage biorelevant dissolution

This post describes best practice use of filters during two stage dissolution testing

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Key requirements for filters used in biorelevant dissolution testing

We recommend the use of glass filters with pre-filters built-in. These filters have excellent efficiency in removing particles and do not leach substances into the biorelevant media.

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What is filter compatibility and why is it so important?

There are two aspects of filter compatibility that the dissolution scientist should consider...

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Sample requirements for a drug filter adsorption study

To conduct a drug filter adsorption study, typically, a sample representing around 10% to 20% of drug release from the immediate-release dosage form in the dissolution vessel is needed.