Syringe Filters
Suitable for biorelevant dissolution testing of most immediate release drugs
High filtration capacity with minimal risk of clogging or bursting
Low drug adsorption and negligible extractables
Glass Microfibre (GMF) or Polypropylene (PP) versions available
Ready for immediate shipment in packs of 60 pieces
Using the right filter for dissolution sampling can make a big difference to your results. When carrying out dissolution runs, samples taken from each vessel at the defined time points must be filtered to remove any undissolved (solid) drug to stop the dissolution process. A suitable filter for dissolution should be efficient, reproducible, have low drug adsorption and not leach extractables, clog or burst. Filter dimensions of 0.45µm pore size and 25mm diameter are generally best for testing drugs with biorelevant media in standard USP vessels.
The syringe filters we sell are manufactured in the UK by Whatman. We have found them to be excellent quality with good flow rate, low hold up volume, low retention and they should not clog, even when sampling very insoluble drugs at later time points. We carry decent stocks of them and they are available in packs of 60 for immediate dispatch.
For testing in FaSSIF and FeSSIF, we recommend the polypropylene version.
For testing in FEDGAS, we recommend the GMF with glass prefilter version.
Specifications:
- Maximum pressure 5.2 bar (75 psi)
- Moderate hold up volume (<250 µl)
- Luer Lock connection (Inlet female, Outlet male)
- Polypropylene filter housing