Calculate the maximum drug concentration if the drug completely dissolves in the dissolution medium (typically 900mL).
The result will be used repeatedly in many subsequent calculators for preparation of standards.
Maximum drug concentration
Calculate the maximum drug concentration if the drug completely dissolves in the dissolution medium (typically 900mL).
The result will be used repeatedly in many subsequent calculators for preparation of standards.
Determine the target concentration which is required to prepare the primary standard (PS).
Primary standard target concentration
Determine the target concentration which is required to prepare the primary standard (PS).
The purpose of the primary standard is to serve as a concentrated standard/stock for subsequent preparation of secondary standard, multiple standards or dilutions of know drug concentrations.
Primary Standard (PS) Preparation
Primary standard (PS)
The purpose of the primary standard is to serve as a concentrated standard/stock for subsequent preparation of secondary standard, multiple standards or dilutions of know drug concentrations.
Primary Standard (PS) Preparation
Secondary standard is required to improve the accuracy of drug concentration and has an intermediate drug concentration. For the preparation of secondary standard, dilution of primary standard is carried out.
Secondary Standard (SS) Preparation
Secondary standard (SS)
Secondary standard is required to improve the accuracy of drug concentration and has an intermediate drug concentration. For the preparation of secondary standard, dilution of primary standard is carried out.
Secondary Standard (SS) Preparation
The highest and lowest drug concentration standards are used to check whether the analytical HPLC method can accurately and reliably quantify the drug at both extremes of concentration. For the preparation of HD and LD, dilution of secondary standard is carried out.
HD and LD preparation
Highest (HD) and Lowest drug (LD) concentration standards
The highest and lowest drug concentration standards are used to check whether the analytical HPLC method can accurately and reliably quantify the drug at both extremes of concentration. For the preparation of HD and LD, dilution of secondary standard is carried out.
HD and LD preparation
