BEST SELLER

FaSSIF/FeSSIF/FaSSGF Powder

  • Make 3 different biorelevant dissolution media (FaSSIF/FeSSIF/FaSSGF) from 1 powder

  • In vitro solubility results in FaSSIF/FeSSIF/FaSSGF help establish a relationship between the biopharmaceutical properties of an oral drug and in vivo absorption

  • In vitro dissolution results in biorelevant media can enable drug developers to identify test formulations with superior dissolution profiles

  • Matching buffer concentrates (sold separately) available for incredibly fast media preparation

  • Use our Media Preparation Tool (see below) for customized instructions

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FFF01 (2.5L size)
FFF02 (25L size)
FFF03 (250L size)
FFF04 (4 x 2.5L size)
FFF05 (4 x 25L size)
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In stock Ready for immediate dispatch
BEST SELLER

FaSSIF/FeSSIF/FaSSGF Powder

  • Make 3 different biorelevant dissolution media (FaSSIF/FeSSIF/FaSSGF) from 1 powder

  • In vitro solubility results in FaSSIF/FeSSIF/FaSSGF help establish a relationship between the biopharmaceutical properties of an oral drug and in vivo absorption

  • In vitro dissolution results in biorelevant media can enable drug developers to identify test formulations with superior dissolution profiles

  • Matching buffer concentrates (sold separately) available for incredibly fast media preparation

  • Use our Media Preparation Tool (see below) for customized instructions

Product Code:
Select Pack
FFF01 (2.5L size)
FFF02 (25L size)
FFF03 (250L size)
FFF04 (4 x 2.5L size)
FFF05 (4 x 25L size)
Quantity
-
+
$
Add to Cart
Need a Quote?
Send Purchase Order
In stock Ready for immediate dispatch
X
Email Purchase Orders to: [email protected]
First orders are on a proforma basis.
Subsequent orders qualify for 30 days net payment terms.
Media Preparation Tool
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Product Description

FaSSIF, FeSSIF and FaSSGF are dissolution media that simulate human gut fluids:

FaSSIF: Fasted State Simulated Intestinal Fluid
FeSSIF: Fed State Simulated Intestinal Fluid
FaSSGF: Fasted State Simulated Gastric Fluid

They contain physiological surfactants (bile salts and lecithin) present in the gastrointestinal tract to simulate these fluids much more accurately than conventional dissolution media. All 3 of these ‘biorelevant’ media can be made from 1 powder and our recently introduced buffer concentrates (sold separately) make their preparation even easier, quicker and more accurate than ever before.

We’ve been producing FaSSIF/FeSSIF/FaSSGF (originally known as ‘SIF Powder’) for more than a decade and it’s trusted by the 10 biggest Pharmaceutical companies in the world as the industrial standard for preparing biorelevant test media. Its versatility and ease of use make it the perfect introduction to biorelevant testing. Here’s why the product is so useful to both new and generic developers of oral drugs:

*In vitro solubility results in biorelevant media help establish a relationship between the biopharmaceutical properties of an oral drug and in vivo absorption

*In vitro dissolution results in biorelevant media can enable drug developers to identify test formulations with superior dissolution profiles

*Ideal for use in USP 1 or USP 2 dissolution apparatus (we recommend 900mL of media per vessel)

*Drug analysis can be carried out by HPLC

*Standardized preparation method is extremely fast and simple and results in highly reproducible media every time

*Get customized instructions explaining how to make different FaSSIF/FeSSIF/FaSSGF volumes from our ‘Media Preparation Tool’ (see above)

*Different pack sizes available to suit your testing requirements (see top of screen)

Frequently bought together with FaSSIF/FeSSIF/FaSSGF Powder
FEDGAS High-Fat Meal Dissolution Kits
 Our turnkey kits enable you to generate dissolution profiles of your drug in fed stomach media (Early, Mid and Late versions available)
FaSSIF Buffer Concentrate
 Use with FaSSIF/FeSSIF/FaSSGF Powder to make FaSSIF of the highest quality and reproducibility in just seconds
FeSSIF Buffer Concentrate
 Use with FaSSIF/FeSSIF/FaSSGF Powder to make FeSSIF of the highest quality and reproducibility in just seconds
FaSSGF Buffer Concentrate
 Use with FaSSIF/FeSSIF/FaSSGF Powder to make FaSSGF of the highest quality and reproducibility in just seconds
Syringe Filters
 We recommend these glass syringe filters manufactured in the UK by Whatman for successful biorelevant testing
Frequently bought together with FaSSIF/FeSSIF/FaSSGF Powder
FEDGAS High-Fat Meal Dissolution Kits
 Our turnkey kits enable you to generate dissolution profiles of your drug in fed stomach media (Early, Mid and Late versions available)
FaSSIF Buffer Concentrate
 Use with FaSSIF/FeSSIF/FaSSGF Powder to make FaSSIF of the highest quality and reproducibility in just seconds
FeSSIF Buffer Concentrate
 Use with FaSSIF/FeSSIF/FaSSGF Powder to make FeSSIF of the highest quality and reproducibility in just seconds
FaSSGF Buffer Concentrate
 Use with FaSSIF/FeSSIF/FaSSGF Powder to make FaSSGF of the highest quality and reproducibility in just seconds
Syringe Filters
 We recommend these glass syringe filters manufactured in the UK by Whatman for successful biorelevant testing