FaSSIF/FeSSIF/FaSSGF

  • Use 3F Powder + Buffer Concentrates to make FaSSIF, FeSSIF or FaSSGF

  • 3F Powder contains bile salts + lecithin to form gastrointestinal mixed micelles

  • Use Media Preparation Tool below for customized preparation instructions

  • Custom Syringe Filters available in packs of 72 pieces

COA FINDER:
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*see pack or invoice

1) Buy Powder:

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1) Buy Powder:

  • 70g of 3F Powder makes FaSSIF (30L) or FeSSIF (6L) or FaSSGF (>1000L)

  • 7g of 3F Powder makes FaSSIF (3L) or FeSSIF (600mL) or FaSSGF (>100L)

3F Powder
FFF02
70g
3F Powder
FFF01
7g
In stock
$499.99
Buy 4, Save 20%
- +
In stock
$139.99
Buy 4, Save 28%
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2) Choose Buffer Concentrate(s):

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FaSSIF= Fasted State Simulated Intestinal Fluid

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FeSSIF=Fed State Simulated Intestinal Fluid

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FaSSGF=Fasted State Simulated Gastric Fluid

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2) Choose Buffer Concentrate(s):

  • Use with 3F Powder to make FaSSIF/FeSSIF/FaSSGF in seconds

FaSSIF Buffer Concentrate
FASBUF
250g
FeSSIF Buffer Concentrate
FESBUF
250g
FaSSGF Buffer Concentrate
FASGBUF
250g
In stock
$29.99
Buy 10, Save 10%
- +
In stock
$29.99
Buy 10, Save 10%
- +
In stock
$29.99
Buy 10, Save 10%
- +

3) Add Syringe Filters:

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3) Add Syringe Filters:

  • For filtration of dissolution samples <5mL we recommend 13mm version

  • For filtration of dissolution samples >5mL we recommend 25mm version

GMF Syringe Filters 13mm
GMF13
72 pieces
GMF Syringe Filters 25mm
GMF25
72 pieces
In stock
$199.99
Buy 8, Save 37%
- +
In stock
$199.99
Buy 8, Save 37%
- +
Media Preparation Tool
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Product Description

FaSSIF, FeSSIF and FaSSGF are dissolution media that simulate human gut fluids:

FaSSIF: Fasted State Simulated Intestinal Fluid
FeSSIF: Fed State Simulated Intestinal Fluid
FaSSGF: Fasted State Simulated Gastric Fluid

They contain physiological surfactants (bile salts and lecithin) present in the gastrointestinal tract to simulate these fluids much more accurately than conventional dissolution media.

We’ve been producing FaSSIF/FeSSIF/FaSSGF (originally known as ‘SIF Powder’) for more than a decade and it’s trusted by the 10 biggest Pharmaceutical companies in the world as the industrial standard for preparing biorelevant test media. Its versatility and ease of use make it the perfect introduction to biorelevant testing. Here’s why the product is so useful to both new and generic developers of oral drugs:

*In vitro solubility results in biorelevant media help establish a relationship between the biopharmaceutical properties of an oral drug and in vivo absorption

*In vitro dissolution results in biorelevant media can enable drug developers to identify test formulations with superior dissolution profiles

*Ideal for use in USP 1 or USP 2 dissolution apparatus (we recommend 900mL of media per vessel)

*Drug analysis can be carried out by HPLC

*Standardized preparation method is extremely fast and simple and results in highly reproducible media every time

*Get customized instructions explaining how to make different FaSSIF/FeSSIF/FaSSGF volumes from our ‘Media Preparation Tool’ (see above)