FaSSIF-V2

  • Use FaSSIF-V2 Powder with matching Buffer Concentrate for instant medium preparation and maximum reproducibility 

  • Use Media Preparation Tool below for customized preparation instructions

  • Custom Syringe Filters available in packs of 72 pieces

COA FINDER:
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*see pack or invoice

1) Buy Powder:

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1) Buy Powder:

  • 55g of powder makes 30 litres of FaSSIF-V2

FaSSIF-V2 Powder
V2FAS
55g
In stock
$499.99
Buy 4, Save 20%
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2) Buy Buffer Concentrate:

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2) Buy Buffer Concentrate:

  • Use with FaSSIF-V2 Powder

  • 280g of buffer concentrate makes 6 litres of buffer solution

FaSSIF-V2 Buffer
V2FASBUF
280g
In stock
$29.99
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3) Add Syringe Filters:

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High filtration efficiency with minimal risk of clogging or bursting

Low drug adsorption and negligible extractables

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X

High filtration efficiency with minimal risk of clogging or bursting

Low drug adsorption and negligible extractables

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3) Add Syringe Filters:

  • For filtration of dissolution samples <5mL we recommend 13mm version

  • For filtration of dissolution samples >5mL we recommend 25mm version

Dissolution Filters 13mm
GMF13
72 pieces
Dissolution Filters 25mm
GMF25
72 pieces
In stock
$199.99
Buy 4, Save 25%
- +
In stock
$199.99
Buy 4, Save 25%
- +
Media Preparation Tool
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Product Description

FaSSIF-V2 is a biorelevant dissolution medium that simulates human fasted state intestinal fluid.  

Although FaSSIF-V2 was introduced after FaSSIF, it is not superior to the original medium. It contains the same physiological surfactants as FaSSIF but in a slightly different bile salt to lecithin ratio.

If you are a new user of biorelevant media, we would recommend you start with our best selling 3F Powder (FaSSIF/FeSSIF/FaSSGF) which enables you to produce 3 different biorelevant media from the same powder (you cannot do so with this FaSSIF-V2 product). Nevertheless, FaSSIF-V2 is still an exceptionally useful testing medium if you are developing an oral drug:

*As with FaSSIF, it can help you gain in vitro insights into drug solubility and dissolution in the small intestine before a meal. Download a step-by-step biorelevant dissolution guide here

*FaSSIF-V2 is described in the recently introduced “USP Chapter <1236> Solubility measurements” as one of the recommended biorelevant media for testing drug solubility in human fasted state simulated intestinal fluid  

*Ideal for use in USP1 or USP2 dissolution apparatus (we recommend 900mL of FaSSIF-V2 per vessel) 

*Drug analysis can be carried out by HPLC. Our dedicated guide will help with your HPLC analytical set up and is available for download here

*Simple and quick preparation method. You can get customized instructions explaining how to make different FaSSIF-V2 volumes from our Media Preparation Tool above