FeSSIF-V2

  • Use FeSSIF-V2 Powder with matching Buffer Concentrate for instant medium preparation and maximum reproducibility

  • Use Media Preparation Tool below for customized preparation instructions

  • Custom Syringe Filters available in packs of 72 pieces

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1) Buy Powder:

  • 60g of powder make 6 litres of FeSSIF-V2

FeSSIF-V2 Powder
V2FES
60g
In stock
$499.99
Buy 4, Save 20%
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2) Buy Buffer Concentrate:

  • 310g of buffer concentrate make 6 litres of buffer solution

FeSSIF-V2 Buffer Concentrate
V2FESBUF
310g
In stock
$29.99
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3) Add Syringe Filters:

  • For filtration of dissolution samples <5mL we recommend 13mm version

  • For filtration of dissolution samples >5mL we recommend 25mm version

GMF Syringe Filters 13mm
GMF13
72 pieces
GMF Syringe Filters 25mm
GMF25
72 pieces
In stock
$199.99
Buy 8, Save 37%
- +
In stock
$199.99
Buy 8, Save 37%
- +
Media Preparation Tool
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Product Description

FeSSIF-V2 is a biorelevant dissolution medium that simulates human fed state intestinal fluid. It is quite similar to FeSSIF but contains lipolysis products of fat digestion. This could help you understand more clearly the solubility and dissolution of lipophilic drugs (Log D ≥ 3) in the fed state intestine in vivo. It’s a very useful tool for new and generic developers of an oral drug:

*FeSSIF-V2 is described in the recently introduced ‘USP Chapter <1236> Solubility measurements’ as a recommended biorelevant medium for testing drug solubility in human fed state simulated intestinal fluid

*Ideal for use in USP 1 or USP 2 dissolution apparatus (we recommend 900ml of FeSSIF-V2 per vessel)

*Drug analysis can be carried out by HPLC

*Simple and quick preparation method

*Get customized instructions explaining how to make different FeSSIF-V2 volumes from our ‘Media Preparation Tool’ (see above)