Dissolution profiles in FeSSIF-V2

Dissolution runs, using USP Dissolution Apparatus 2, were carried out at 37°C with 900mL of the FeSSIF-V2 media, prepared using the Buffer Concentrate (N=6 vessels) and the buffer from scratch (N=6 vessels), separately, for each drug.

The dissolution profiles are very similar between both media for all of the drugs tested.