Which solutions are required to check for interference
The following solutions should be tested to check for interference.
Prepare diluted samples of:
• biorelevant medium
• drug without biorelevant medium (use secondary standard solution and dilute with diluent to prepare same drug concentration as working standard solution)
• drug with biorelevant medium
• dosage form (e.g. drug and excipients) with biorelevant medium
Download our Biorelevant Dissolution Guides here.