What are the benefits of using Biorelevant Mini Prep Kits?
Background
To ensure reproducibility of FaSSIF, FeSSIF and FaSSGF for low volume preparation, Biorelevant Mini Prep Kits have been developed and are now available for purchase on our website. They are ideal for solubility experiments as well as low volume dissolution studies, particularly for new chemical entities.
What is Mini Prep Kit
Each Mini Prep Kit is composed of 6 single use vials containing the precise amount of 3F Powder and 6 mini bottles of corresponding Buffer Concentrate to prepare 6 x 100mL of the specific Biorelevant Medium you want.
Benefits of using Biorelevant Mini Prep Kits
• Single use
Single use vials not only have the precise amount of powder but also crucially always have excellent quality fresh 3F Powder to prepare consistent Fasted and Fed State Intestinal Fluids (FaSSIF, FeSSIF) and Fasted Gastric Fluid (FaSSGF). Single use vials eliminate potential risk of 3F Powder ageing that can occur 4 weeks after first opening of the multi-use packs. Particularly for precipitation and supersaturation studies, aged powder can lead to inaccurate and variable experimental data.
• Storage
Both 3F Powder and Buffer Concentrate should be stored at room temperature and are stable for at least 12 months.
• Reproducible media & accurate results
Mini Prep Kits enable the preparation of consistent media with defined and consistent pH, osmolarity and particle size resulting in better quality reproducible results.
• Rapid and easy to use
Mini Prep Kits are the perfect solution to make smaller volumes of consistent Biorelevant Media, rapidly and easily using a standard preparation technique and standardised components.
Conclusion
Mini Prep Kits are ideal for rapidly and efficiently preparing smaller volumes of reproducible media for Biorelevant Solubility experiments.
Guides for the HPLC analytical Set up and how to carry out a Biorelevant Solubility Experiment can be downloaded here.































