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Maximum Drug Concentration
Calculate the theoretical maximum concentration of drug dissolved in a dissolution vessel if the drug is completely released from the dosage form. This result is important to know when you are preparing standards for HPLC analysis
Target Concentration for Primary Standard
Determine the target drug concentration which required to prepare the Primary standard
Prepare Primary Standard (PS)
Accurately weigh the “Amount of drug substance for Primary Standard” into a volumetric flask and dissolve with organic solvent. This will provide the Primary standard concentration
Prepare Secondary Standard (SS)
Calculate the required volume of primary standard needed to prepare the Secondary standard and calculate the conentration of Secondary standard
Prepare Standards with Highest and Lowest Drug Concentration
Select the dilution ratio approximately and calculate the required volume of secondary standard in order to prepare the highest(≈120%) and lowest(≈5%) Standard
The selected dilution ratio should work with highest(≈120%) and lowest(≈5%) concentrations of Standard
Mass/Volume Unit Converter
Use calculator to convert mass/volume units
Mass/Volume Concentration to Molarity Calculator
Calculate Molarity (molar concentration) by dividing the mass/volume concentration of compound by its molecular weight.
Molarity Unit Converter
Use calculator to convert molarity units
Mass <-> Moles Calculator
Use this calculator to convert between mass and moles of a compound.
Calculate Mass from Molarity
Calculate the required mass of compound in a specific volume of solvent to achieve the target molarity (molar concentration).
Volume Unit Converter
Use calculator to convert mass units
Mass Unit Converter
Use calculator to convert mass units
We tested the 'FaSSIF/FeSSIF/FaSSGF' media for our research. The results were as desired. We will continue to buy the product.
It took only 10 minutes to prepare FaSSIF, this powder makes it easy to use biorelevant media.
The powder from biorelevant.com provides a very practical and economical way to produce the FaSSIF medium.
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Service is the best, efficient and reliable. The powder from biorelevant.com is the ONLY material that we use.
Dog FaSSIF/FaSSGF helped us to select one formulation out of several prototypes for a bioavailability study in dogs. All prototypes were tested in buffer media in advance but results were hardly discriminative due to the poor solubility of the API. We expect that the canine Biorelevant Media will also reflect the in vivo precipitation kinetics of APIs more accurately if enhanced solubility (supersaturation) is targeted.
I think that FaSSIF is a very special and original product and it's very important for our lab research to help create new medicines.
I think it's a good product for researching new medicines. Thanks for your work!
It is easy to use. The powder is not irritating when weighing. The containers (packaging) are very
attractive. We are very satisfied with your product.
FaSSIF/FeSSIF/FaSSGF powder is very easy to use and gives consistent, reliable results. Instructions for use are very clear and correspondence from the company is swift and helpful. Great service too.
We use powder from biorelevant.com for in vitro dissolution testing of the drugs in Biorelevant Media and it is very helpful to predict the in vivo behaviour of the drugs in this way. Preparation of the media is very easy and time saving with this powder.
Trying to convince people that we should use biorelevant media in order to accurately predict the in vivo situation is one thing, but knowing that these media are also easy to make should convince everybody to work with it. Even in fed state media (where we are dealing with a complex intraluminal environment), biorelevant.com has now launched the new FeSSIF-V2 which can lead to more optimized predictions in postprandial conditions.
We use the powder for preparation of different biorelevant media (FaSSGF, FaSSIF and FeSSIF) for solubility and dissolution studies. The method of preparation of the media is very easy to follow and we get biorelevant media of high quality. The short time needed for their preparation and the reproducibility of the media are great advantages of this product. The support from the biorelevant.com team is excellent!
We routinely use powders from biorelevant.com in our transfer model to examine the supersaturation and precipitation behaviour of poorly soluble drugs. Not only is the media considerably quicker to prepare but its preparation is also significantly safer as dichloromethane is no longer required. We have been very happy using the media so far and will continue to use the powders in the future.
Now there is only one way of preparation for us – FaSSIF/FeSSIF/FaSSGF, because there are only benefits. It saves a lot of time (by our calculations more than 50%) and the best part is very simple preparation. It's also very user friendly because with powder we can prepare low volumes of media (e.g. for solubility testing).
Biorelevant.com media have been a staple of our lab for the past year as we move into oral formulation development and testing. Your powders are easy to use, and the buffers are straightforward to make. I appreciate the ease with which we can make intestinal and gastric fluids for research purposes.
The products are perfect... we are very pleased with them and the service offered.
Great products with simple preparation procedures to help preclinical and clinical formulation work such as solubility measurement and dissolution testing.
Products are easily applicable. Everything about our order was fast and professional.
These products are great!
I like the products very much. They are good for my analysis when simulating intestinal fluids.
Meets expectations. Easy preparation. Fast delivery, simple instructions. The more compact bottle needs less space in the fridge. The webpage with calculations is appreciated.
I think that the products offered are great for development work on dissolution method and the ease of use of the product provided made buying from your company a must for future method development. Service was extremely fast.
My group has been using the media since before I joined. The products have been very easy to use and quick to arrive. It's been super easy ordering from you guys.
Perfect for our dissolution work... the products are great with delivery always on time. Guys, keep up your good job!
I've always gotten reliable and reproducible data with the products that helped the formulations department better adjust their experiments to produce desired dissolution profiles. Love the wide range of media as well!
I think these products are great. We have some simulated solutions we make but this is great for adding some components that we don't normally use. I also like that the same product can be used for fed and fasted intestinal conditions with different prep.
FaSSIF-V2 is very user friendly. Good explanation on the preparation and the fast delivery is very appreciated!
The powder is really good to show how API´s and formulations work under biorelevant conditions. It is easy to use and handle. We test many API´s with powder from biorelevant.com and have had good results.
We use FaSSIF/FeSSIF/FaSSGF powder in our lab. The biggest benefit of using the powder is that it is very flexible and compatible with different buffers. We can then create Biorevelant Media at different pHs and buffer capacities. The powder is very easy to use. The biorelevant.com website provides a great resource in terms of preparing and using the media. The staff are very friendly and work efficiently!
