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Biorelevant Mini Prep Kits

FaSSIF/FeSSIF/FaSSGF

FEDGAS (Early/Mid/Late)

Canine FaSSIF/FaSSGF

Biorelevant Dissolution Filters

Biorelevant Solubility Filters

Gastro-Duodenal Media

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HPLC Calculators

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Learning Centre

ALL NEW! Background Biorelevant media Analysis Filters Dissolution Solubility Drugs in Biorelevant Media

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Filters for biorelevant solubility testing

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Why is it recommended to use Biorelevant products within 1 month of opening?

Biorelevant media

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What are the benefits of using Biorelevant Mini Prep Kits?

Biorelevant media

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Gefitinib two stage dissolution comparison (Biorelevant vs Non-biorelevant)

Drugs in Biorelevant Media

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Two stage biorelevant dissolution of Stugeron® (cinnarizine 15 mg)

Drugs in Biorelevant Media

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Two stage biorelevant dissolution

Biorelevant media

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pH reproducibility of two Stage biorelevant dissolution kit

Biorelevant media

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Filters for two stage dissolution testing

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Discriminatory dissolution potential of FEDGAS for Xarelto® (Rivaroxaban) 20 mg film-coated tablets

Drugs in Biorelevant Media

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Discriminatory dissolution potential of FEDGAS for Celecoxib 200mg hard gelatine capsules

Drugs in Biorelevant Media

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Biorelevant dissolution of Invokana® (canagliflozin) film coated tablets

Drugs in Biorelevant Media

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Dissolution of Exemestane 25mg tablets in Biorelevant medium

Drugs in Biorelevant Media

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Importance of filtration in dissolution sample preparation for HPLC analysis

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When is a filter adsorption study necessary?

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Single vs repeated use of filters for two stage biorelevant dissolution

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What is simulated intestinal fluid USP (with or without enzyme)?

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A comparison of USP-SIF (sp) with biorelevant FaSSIF medium

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What are Gastric fluid, simulated, TS (Test Solution) and USP-SGF (sp)?

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USP <1236>: Solubility Measurements Chapter

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What is equilibrium solubility of a drug?

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What is supersaturation of a drug substance?

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What is the difference between a drug product and a drug substance?

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How can biorelevant media be discriminatory?

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Biorelevant Dissolution Test Method

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How Biorelevant Media can help develop generic drugs

Biorelevant media

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How Biorelevant Media can help develop new drugs (NCEs)

Biorelevant media

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The importance of using Biorelevant's Buffer Concentrates

Biorelevant media

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pH reproducibility of FaSSIF/FeSSIF/FaSSGF made from 3F Powder + Buffer Concentrates

Biorelevant media

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What is FaSSIF?

Biorelevant media

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What is the composition of FaSSIF?

Biorelevant media

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What is FeSSIF?

Biorelevant media

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What is the composition of FeSSIF?

Biorelevant media

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What is FaSSGF?

Biorelevant media

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What is the composition of FaSSGF?

Biorelevant media

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What is a High-Fat FDA meal?

Biorelevant media

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How can food affect drugs in the fed stomach?

Biorelevant media

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What is FEDGAS?

Biorelevant media

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What is the composition of FEDGAS?

Biorelevant media

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FeSSGF vs FEDGAS: a comparison

Biorelevant media

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Which ingredients are in FaSSIF-V2 Powder?

Biorelevant media

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Biorelevant's improved buffer for FaSSIF-V2

Biorelevant media

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HPLC parameters using FaSSIF-V2

Biorelevant media

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Dissolution profiles in FaSSIF-V2

Biorelevant media

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Which ingredients are in FeSSIF-V2 Powder?

Biorelevant media

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An improved Buffer Concentrate for preparation of FeSSIF-V2

Biorelevant media

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HPLC Parameters using FeSSIF-V2

Biorelevant media

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Dissolution profiles in FeSSIF-V2

Biorelevant media

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What is Canine FaSSIF and Canine FaSSGF?

Biorelevant media

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The BCS (Biopharmaceutical Classification System)

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Key requirements for filters used in biorelevant dissolution testing

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What is filter compatibility and why is it so important?

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Sample requirements for a drug filter adsorption study

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How to analyse your drug in Biorelevant Media

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HPLC mobile phase selection for biorelevant samples

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HPLC column selection for analysing samples containing biorelevant medium

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What is a diluent?

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Why Biorelevant Dissolution samples should be diluted for HPLC analysis

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What is Maximum drug concentration calculator?

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How to dilute and prepare standards

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What is Primary standard target concentration calculator?

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What is Primary standard (PS) calculator?

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What is Secondary standard (SS) calculator?

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What is Highest (HD) and Lowest drug (LD) concentration standards calculator?

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Which dilution ratio to select for HPLC analysis

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How to examine compatibility and dilution ratio of diluent with Biorelevant Media

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How to dilute your secondary standard (SS) and dissolution samples with 1:10 dilution ratio whilst keeping the same matrix

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Why include Biorelevant Media in working standards (WS)

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Selecting the drug concentration range of linearity standards (LS)

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Which solutions are required to check for interference

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What is 'specificity'?

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What is 'precision'?

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Why are specificity and precision required with biorelevant media?

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When are specificity and precision required when testing drugs in biorelevant media using HPLC??

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How many HPLC injections are needed when carrying out specificity and precision?

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How to prepare working sample of dosage unit(e.g. drug and excipients) with biorelevant medium to check interference

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Coning of immediate release drug products in a USP 2

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Checking interference by injecting the dosage form in biorelevant medium

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What are the signs of coning

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What to do if the retention time of a drug is reduced during HPLC analysis

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PEAK (Apex) dissolution vessels

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Which factors can increase the retention time of an analyte during HPLC analysis

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How to apply a washing cycle when running an HPLC sequence

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Signs of column deterioration

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How to store HPLC columns after using Biorelevant Media

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What are ghost peaks and why do they occur?