Food Effects & the Fed Gastric Medium

The gastrointestinal juices in the stomach, small intestine and colon are highly complex and variable. A large factor in their variability is the prandial […]

Biorelevant Dissolution, Biorelevant Solubility, Drug Development, Fasted/Fed States, Generic Drugs, Improving Bioavailability

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How GSK Used Biorelevant Media

How GlaxoSmithKline (GSK) used Biorelevant Media (FaSSIF, FeSSIF and FaSSGF) to improve the solubility and dissolution of their novel drug danirixin for improved bioavailability. […]

Biorelevant Dissolution, Biorelevant Solubility, Fasted/Fed States, Improving Bioavailability, Industrial Use, NCEs

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Drug Substance vs. Drug Product

The difference between ‘drug substance’ and ‘drug product’ is important to understand and can really help with the successful development of your pharmaceutical drug. […]

Biorelevant Dissolution, Biorelevant Solubility, Drug Development, IVIVC

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The Importance Of Fasted + Fed States

Explaining the difference between ‘fasted’ (without food) and ‘fed’ (with food) states and how they impact on the solubility and dissolution of a drug.  […]

Biorelevant Dissolution, Biorelevant Solubility, Fasted/Fed States

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